biological effectiveness of JRR-4 epithermal neutron beam; Experiment under free air beam and in water phantom (Cooperative research)

Yamamoto, Tetsuya*; Yamamoto, Kazuyoshi; Matsumura, Akira*; Kumada, Hiroaki; Kishi, Toshiaki; Hori, Naohiko; Torii, Yoshiya; Horiguchi, Yoji; Nose, Tadao*

JAERI-Research 2002-011, 56 Pages, 2002/05

JAERI-Research-2002-011.pdf:3.17MB

The surviving curve and RBE of dose components generated in boron neutron capture therapy (BNCT) were separately determined in neutron beams at JRR-4. Surviving fraction of V79 cell with or without B was obtained using an epithermal neutron beam (ENB), a mixed thermal-epithermal neutron beam (TNB-1), and a thermal neutron beam(TNB-2), which were used or planned to use for clinical trial. The cell killing effect of these beams depended highly on the neutron beam used, according to the epithermal and fast neutron content in the beam. RBE of the boron capture were 3.990.24, 3.040.19 and 1.430.08, RBE of the high-LET dose components based were 2.500.32, 2.340.30 and 2.170.28 for ENB, TNB-1 and TNB-2, respectively. The experimental determination of biological effectiveness factor outlined in this paper is applicable to the dose calculation for each dose component of the neutron beams and contribute to an accurate RBE as comparison with a neutron beam at a different facility employed in ongoing and planned BNCT clinical trials.

Annual report of Department of Research Reactor 1999; April 1, 1999 - March 31, 2000

Department of Research Reactor

JAERI-Review 2000-036, 263 Pages, 2001/03

JAERI-Review-2000-036.pdf:19.89MB

no abstracts in English

Annual report of Department of Research Reactor 1997; April 1, 1997 March 31, 1998

JAERI-Review 98-027, 205 Pages, 1999/01

JAERI-Review-98-027.pdf:8.95MB

no abstracts in English

Experimental data on polyethylene shield transmission of quasi-monoenergetic neutrons generated by 43- and 68-MeV protons via Li(p,n) reaction

Nakao, Noriaki*; Nakashima, Hiroshi; Nakao, Makoto*; Sakamoto, Yukio; Nakane, Yoshihiro; ; Tanaka, Shunichi; Nakamura, Takashi*

JAERI-Data/Code 98-013, 46 Pages, 1998/03

JAERI-Data-Code-98-013.pdf:2.14MB

no abstracts in English

Annual report of Department of Research Reactor 1995; April 1, 1995 March 31, 1996

JAERI-Tech 97-059, 177 Pages, 1997/12

JAERI-Tech-97-059.pdf:5.96MB

no abstracts in English

Annual report of Department of Research Reactor 1994; April 1, 1994 March 31, 1995

JAERI-Tech 95-047, 170 Pages, 1995/10

JAERI-Tech-95-047.pdf:7.67MB

no abstracts in English

Annual report of Department of Research Reactor 1992; April 1, 1992 March 31, 1993

JAERI-M 93-226, 229 Pages, 1993/12

JAERI-M-93-226.pdf:9.03MB

no abstracts in English

Palse Neutron Generation(Pulse Width : over 0.5sec) with JAERI 2MV VdG

;

JAERI-M 5523, 22 Pages, 1974/01

JAERI-M-5523.pdf:0.79MB

no abstracts in English